I know this won't help you at all, but maybe you should use only one or two active disciplines. Bloddlines itself wasn't made for more than that, anyway. I prefer two-three "basic" ones (like Celerity, Potence and the like) and only one active, with multiple powers. Regarding the mod, that's sad, hope you can make it through.
Do you still have problems having started over without CE? Or are you using the same save file? You probably know it by now, since you've beaten the game many times, but it's not a good idea to play a save file in different mods/mod versions.
What game version do you have? Steam, GOG or retail?
Belzelga
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