I usually do small mods for myself...

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Tough Important NPCs and Companions [1.5.1]

Tough Important NPCs and Companions [1.5.1]

S.T.A.L.K.E.R. Anomaly Prefab 35 comments

Makes unique NPCs and companions able to sustain more damage.

Less Ammo From Unloading 1.0 [1.4.22]

Less Ammo From Unloading 1.0 [1.4.22]

S.T.A.L.K.E.R.: Call of Chernobyl Singleplayer Map 7 comments

This addon simply makes it so you get less ammo when unloading guns from NPCs.

Limited Game Saving 1.0 [1.4.22]

Limited Game Saving 1.0 [1.4.22]

S.T.A.L.K.E.R.: Call of Chernobyl Singleplayer Map 15 comments

If you find Ironman mode too tough but the normal game too easy, try this out!