Sixty years after the first game, BloodRayne stalks a modern day city, hunting down each of her nefarious siblings. They have banded together and form ed the Cult of Kagan, pledging to carry on the legacy of their dead father to create a new era of vampire supremacy where humans are mere cattle for blood thirsty predators. The Cult has produced "The Shroud", a mysterious substance which, when released, renders the sun's lethal rays harmless to vampires. Now only BloodRayne stands between an unsuspecting humanity and a horrifying vampire dawn.