I can't really but what I noticed is that it usually starts happening when lots of lighting effects are on the screen (you get shot at, barrels blow up etc.). I disabled self parallax and that solve it but I don't know if that was the issue or it simply freed up enough fps that I don't notice the dip when the effects parade hits (I'm playing at a vsynced 60).
And no, I don't have any specific driver settings turned on, AA is done through Q2XP's FXAA.
Zaxx233
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