Thanks for that, MasterThief. I looked at the forums and the wiki pages and tried making many minor changes in the path in the helper command files, but one thing missed me in the instructions.
The taffing tilde.
I am a relatively new Mac user so the tilde in the instructions wasn't clear to me. It would probably be best to change it to the full path in the instructions here and on the wiki.
For others like me - The little ~ in the directory means your Doom 3 folder should be in the /Users/USERNAME/Library/Application Support/ folder and NOT the /Library/Application Support folder.
BUT, this still won't relaunch TDM automatically. Once TDM quits after you press Install Mission, you have to use the tdmlauncher_helper.command
Tafferer
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I am a 3D artist. I write, animate, model, rig, texture, render, and light.