Pyxenos has been patched with a small bug fix update. Now the game supports a bigger range of screen resolutions and can be played with AZERTY keyboards.
To enable AZERTY mode open config.cfg in notepad. The file is located at the installation directory, by default should be either C:\Program Files\Desura\Common\pyxenos or C:\Program Files (x86)\Desura\Common\pyxenos.
Once file is open change line keys_azerty=0 to keys_azerty=1 and start the game. If file config.cfg doesn't exist please start the game and exit to create it.