1982. Hungering for revenge, the Soviets launch a full-scale invasion against the United States of America. The Allied primary defense network is shut down under mysterious circumstances and the only thing between the Soviets and America is a tiny little ocean. The third Great World War begins, where the strings are pulled by a single man - a remnant of Stalin's psychic legacy. This war begins anew. But at this moment suddenly appeared hidden enemy who called the Brotherhood of Nod, headed by Kane. Getting Nod attacked the city, but soon came to a full-scale attack to the spread of Tiberium. The threat of the two parties, the alliance created organization Global Initiative Defense for protection from enemies and Tiberius. But soon realize that there are other parties who hide in the darkness and waiting for the right moment of the day take over the world or revenge.