SWAT goes deep into the house through a glass door (disguised as a mirror) to train, where they get to the underground laboratory. It turns out that the train took them to the "ant hill" - the secret laboratory corporation «Umbrella», situated near the town of Raccoon City, which conducted the study of viruses. Getting to the quarters, "Red Queen", the special forces disable it. As a result, all the closed doors were opened to release the entire indoctrinate personnel. Zombie attack survivors and if one of them is bitten, it has a few minutes to find and enter an antidote, otherwise a member of the command dies ... The game is presented in survival mode, ie players must escape of zombies as they can, core of the game relies on multiplayer.